AWWA WQTC58787 A New Breakthrough Process Using DNA Chip Technology for Controlling the Microbiological Quality of Water

Conference Proceeding by American Water Works Association, 11/02/2003

Guillot, Emmanuelle; Courtois, Sophie; Renaud, Patricia; Maury, Elise; Vachon, Carole; Lacroix, Bruno; Bulteau, Stephane; Armand, Marie-Astrid; Mabilat, Claude

Full Description

An industrial partnership between SUEZ ENVIRONNEMENT and BIOMERIEUXSA was established in order to jointly develop the first analytical process in the world usingDNA chip technology, powered by Affymetrix, Inc. technology, which allows themultidetection of bacteria, parasites, and viruses in water samples in less than a day. TheGeneChip brand technology supplied by Affymetrix (California) is an established, proventechnology that constitutes a major breakthrough for this application since it allows rapidmultidetection of pathogens in one single analysis instead of several monodetection tests.This research program developed a prototype, which represents a complete analytical processfrom a 30L water sample preparation to the multidetection of 13 microorganisms. Researchhas come up with the product and reagents for sample preparation, choice of the genomicsequences, and development of the bio-informatics algorithm for multidetection.The speed of this new process (less than a day as opposed to weeks for viruses) and the specific multidetection of viable waterborne pathogens will make it possibleto assess and protect against potential risks in a better way. It will also improve decision-makingabout the best treatments to use and allow faster return to normal operations whetherin the municipal, tertiary (public buildings, hospitals, etc.) or industrial sectors (Food andBeverage, Cosmetics, Pharmaceuticals, etc.).This new process will enhance the consumer's safety byallowing much faster and better evaluation of potential risks. It will also bring new knowledgeon the occurrence of microorganisms along the water cycle, allowing better decision-making to ensure water sustainability. Includes 30 references, table, figures.

Product Details

Edition: Vol. - No. Published: 11/02/2003 Number of Pages: 11 File Size: 1 file , 390 KB